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February 5, 2026Annals of the National Academy of Medical Sciences (India)0 citationsOpen Access

Apparent brain death in snakebite: A reversible neurotoxic crisis

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TBTidip BordoloiAKAlisha KhanAAAmitesh Aggarwal

Key Points

  • To highlight the reversible effects of neurotoxic snake bites that can mimic brain death and to advocate for careful assessment in such cases.
  • Presented a case of a patient with neuroparalytic symptoms following a snake bite.
  • Administered polyvalent snake antivenom as the main intervention.
  • Provided supportive care including ventilatory support during recovery.
  • Patient showed full neurological recovery after treatment with antivenom.
  • Symptoms of brain death were resolved with timely medical intervention.
  • Emphasized the need for differentiating between actual brain death and neurotoxic effects of snake bites.

Abstract

In the field of toxicology, snake bites are recognized as a significant cause capable of mimicking brain death. A neurotoxic snakebite can manifest with a wide range of symptoms, causing asymptomatic cases to more severe presentations. Common symptoms include ptosis and complete external and internal ophthalmoplegia, which indicate paralysis of the eye muscles. In severe cases, the bite can lead to complete respiratory failure, necessitating urgent medical intervention. Here, we present a patient with a neuro paralytic snake bite with conditions mimicking brain death. The patient achieved full neurological recovery following treatment with polyvalent snake antivenom and supportive care. This case underscores the importance of considering the neuroparalytic effects of snake bites when assessing patients, as it may lead to a false diagnosis of brain death. Intensivists should carefully evaluate these potential effects before deciding to withdraw ventilatory supp]ort or consider organ donation.

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Cite This Study

Bordoloi et al. (2026) studied this question.

synapsesocial.com/papers/69843553f1d9ada3c1fb40eahttps://doi.org/10.25259/anams_148_2025
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