Abstract Introduction/Objectives The relationship between sleep quality and sexual health, particularly erectile dysfunction (ED), has garnered increasing attention in the scientific literature. Sleep disorders such as insomnia and obstructive sleep apnea (OSA) frequently coexist within the condition known as COMISA, thereby elevating the risk of ED. This study aims to assess the prevalence of ED associated with poor sleep quality among young Peruvian university students, emphasizing the importance of integrated approaches to improve both sexual and sleep health. Materials and Methods A cross-sectional analysis was conducted involving university students, utilizing validated scales to evaluate sleep quality, presence of COMISA, and ED. Pathophysiological factors such as hormonal alterations and endothelial dysfunction, as well as psychosocial factors, were considered. The sample comprised young Peruvian individuals, allowing for analysis of correlations between variables and the influence of environmental and mental health factors. Results The prevalence of poor sleep quality was 50.9%, with 93.3% of these individuals exhibiting some degree of ED, predominantly mild (72.7%). Poor sleep quality increased the risk of ED by more than sixfold (p 0.001), even after adjusting for confounding factors. COMISA was associated with physiological alterations, including endothelial dysfunction, decreased testosterone levels, and autonomic imbalances, which contribute to ED. Additionally, psychosocial factors such as stress and anxiety exacerbated the condition. Conclusions Poor sleep quality, especially in the presence of COMISA, is strongly associated with ED among young university students. Interventions to improve sleep, combined with mental health strategies, may be effective in preventing and managing ED. Universities should implement integrated assessment and intervention programs that promote both sexual and sleep health concurrently. Financing No conflict.
Rego et al. (2026) studied this question.