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March 30, 2014European Heart Journal60 citationsOpen Access

High-sensitivity cardiac troponin T and cognitive function and dementia risk: the atherosclerosis risk in communities study

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ASAndrea L.C. SchneiderARAndreea M. RawlingsASA. Richey Sharrett

Key Result

Elevated baseline hs-cTnT levels were linked to lower cognitive test scores and increased risk of dementia hospitalization over follow-up.

Structured PICO

Are elevated baseline concentrations of high-sensitivity cardiac troponin T associated with lower cognitive function and increased dementia risk?

P
Population
Participants in the Atherosclerosis Risk in Communities study
I
Intervention
Elevated baseline concentrations of high-sensitivity cardiac troponin T (hs-cTnT)
O
Outcome
Cognitive test scores at baseline and dementia hospitalization risk during follow-uphard clinical

Subclinical myocardial injury, as indicated by elevated hs-cTnT, is associated with worse cognitive function and an increased risk of dementia hospitalization.

Abstract

Elevations in baseline concentrations of hs-cTnT were associated with lower cognitive test scores at baseline and increased dementia hospitalization risk during the follow-up. Our results suggest that subclinical myocardial injury is associated with cognition and dementia.

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Cite This Study

Schneider et al. (2014) studied this question. Elevated baseline hs-cTnT levels were linked to lower cognitive test scores and increased risk of dementia hospitalization over follow-up.

synapsesocial.com/papers/6984fac5033993fc11890af5https://doi.org/10.1093/eurheartj/ehu124
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