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February 6, 2026Medical Sciences0 citationsOpen Access

Nutritional and Microbiological Aspects of the Formulations and the Impact of Home Enteral Nutrition Therapy Use on Patients’ Quality of Life

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GAGraciele Magda de AlmeidaMEMariana Buranelo Egea

Key Points

  • The aim is to assess nutritional and microbiological aspects of diets used in home enteral nutrition therapy and their impact on quality of life.
  • Cross-sectional, descriptive, observational study design.
  • Evaluated patients through semi-structured interviews and 24-hour dietary recall.
  • Microbial characteristics assessed via microbiological analyses of diet samples.
  • 72.7% of participants used gastrostomy for administration.
  • 54.5% of patients primarily used commercial formulas.
  • Observed complications included 72.7% experienced diarrhea and 77.7% mechanical issues.
  • 91% of participants rated their quality of life as acceptable despite challenges.

Abstract

Background/Objectives: Home Enteral Nutrition Therapy (HENT) is widely used for patients with preserved gastrointestinal function who cannot maintain adequate oral intake. It can be administered through commercial formulas (CF) or artisanal preparation (AP). Methods: This was a cross-sectional, descriptive, observational study with a quantitative and qualitative approach, conducted through semi-structured interviews by the researcher herself. Patients using HENT were evaluated for nutritional status using a 24 h dietary recall, and their quality of life was assessed using a questionnaire administered during an interview with the patient and/or caregiver. Microbial characteristics of the diets were evaluated by collecting samples and performing microbiological analyses according to standard methods. Results: 22 patients participated, mostly elderly, bedridden, and dependent, with gastrostomy as the primary method of administration (72.7%) and CF as the most commonly used (54.5%). AP consisted of cooked vegetables, legumes, milk, oil, and salt, and showed low nutritional diversity and a high risk of microbiological contamination due to manual handling. Frequent complications included diarrhea (72.7%) and mechanical complications (77.7%). Despite these issues, 91% of participants rated their quality of life as acceptable. Conclusions: HENT posed significant challenges to nutritional adequacy and microbiological safety, particularly among patients using artisanal preparations. These findings highlight the need for systematic monitoring and individualized adjustments by a multidisciplinary team, along with structured caregiver training, to optimize intake, reduce complications, and improve the quality and safety of home-based enteral therapy.

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Cite This Study

Almeida et al. (2026) studied this question.

synapsesocial.com/papers/698586118f7c464f23009f7dhttps://doi.org/10.3390/medsci14010071
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