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February 8, 2026Food & Function1 citations

Cyanidin-3-O-glucoside promotes late-stage venous thrombus resolution in mice, accompanied by reduced macrophage M1-associated inflammation and attenuated HIF-1α-linked signaling

YSYu-He ShenZNZhou-Yu NieJZJia-Qi Zhang

Key Points

  • The study aims to investigate the effects of cyanidin-3-O-glucoside on venous thrombus resolution and associated inflammation.
  • Utilized a mouse model of deep vein thrombosis
  • Administered cyanidin-3-O-glucoside
  • Analyzed macrophage polarization
  • Evaluated HIF-1α signaling pathways
  • Cyanidin-3-O-glucoside significantly promoted late-stage thrombus resolution
  • Reduced macrophage M1-associated inflammation was observed
  • Attenuated HIF-1α-linked signaling pathways were noted in treated mice

Abstract

Deep vein thrombosis (DVT) is characterised by thrombus formation in the deep veins, and efficient thrombus resolution is essential to restore venous patency and prevent life-threatening complications. Cyanidin-3-O-glucoside (C3G), a...

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Cite This Study

Shen et al. (2026) studied this question.

synapsesocial.com/papers/698827b40fc35cd7a884694dhttps://doi.org/10.1039/d5fo05273d
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