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February 8, 2026Cancer MedicineOpen Access

Enhancing Quality of Life of Proximal Gastrectomy: A Comprehensive Review of Anastomotic Innovations and Challenges

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Authors

LLLinchuan LiDZDexu ZhangSSSiyi Song

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Overview

Narrative review analyzes reconstructive techniques after proximal gastrectomy, emphasizing quality of life improvements.

Key Points

  • This review examines reconstructive techniques following proximal gastrectomy to improve quality of life postoperatively.
  • Conducted a narrative review of comparative, prospective, and retrospective studies.
  • Analyzed reconstructive techniques for proximal gastrectomy and associated complications.
  • Evaluated outcomes such as reflux esophagitis, anastomotic stenosis, and nutritional parameters.
  • Esophago-gastrostomy had the highest reflux rates at 18%-55% and stenosis rates of 1.1%-27.8%.
  • Anti-reflux modifications like double-flap technique reduced reflux rates to 2%-16.7%, but with increased stenosis risks.
  • Jejunal interposition had reflux rates of 2.1%-100% and stenosis at 0%-31.8%, requiring multiple anastomoses.
  • Double-tract reconstruction showed promising anti-reflux outcomes but may increase costs and surgical time.

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/698828010fc35cd7a8847282https://doi.org/10.1002/cam4.71554
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reconstruction After Proximal Gastrectomy for Adenocarcinoma of the Esophagogastric Junction: Current Evidence, Comparative Outcomes, and Future Perspectives2026
  2. 2Short‐ and Mid‐Term Outcomes of Proximal Gastrectomy With Double‐Tract Reconstruction Versus Total Gastrectomy in Early‐Stage Proximal Gastric Cancer2025 · 1 citations
  3. 3Applications on proximal gastrectomy with gastroesophageal muscular flap anastomosis in laparoscopic surgery: a narrative review2026
  4. 4Trapezoidal tunnel intracorporeal esophagogastric anastomosis technique in laparoscopic-assisted proximal gastrectomy: technical notes and preliminary experience2026
  5. 5Kamikawa anastomosis in proximal gastrectomy for gastric cancer: A systematic review and meta-analysis2025