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February 8, 2026Journal of Drugs in Dermatology0 citations

Pentoxifylline as a Steroid-Sparing Agent in Granuloma Annulare: A Rural Retrospective Study

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WSWilliam T SniderTFTaylor FleshmanRHRebecca Hicks

Key Points

  • Investigate the effectiveness of pentoxifylline as a potential treatment for granuloma annulare.
  • Conducted a retrospective analysis of patients with generalized granuloma annulare.
  • Evaluated the efficacy of pentoxifylline as a treatment.
  • Assessed the comorbidity burden in patients.
  • Pentoxifylline showed favorable efficacy in treating treatment-resistant granuloma annulare.
  • The treatment may serve as a first-line systemic agent for refractory cases.
  • Further multi-center studies are recommended to confirm findings.

Abstract

Generalized GA is more treatment-resistant and associated with a greater comorbidity burden. Pentoxifylline demonstrated favorable efficacy and may serve as a first-line systemic agent in refractory cases. Further multi-center studies are needed to validate these findings and guide evidence-based management of GA.  .

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Cite This Study

Snider et al. (2026) studied this question.

synapsesocial.com/papers/698828010fc35cd7a88472a5https://doi.org/10.36849/jdd.9304
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