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February 8, 2026Materials Horizons1 citations

Supramolecular Net-Suppressor drives tumor vascular-immune microenvironment remodeling with spatiotemporal synchronization for Renal Cancer Therapy

LWLu WangJWJiaqi WangXJXiao Jin

Key Points

  • This research aims to explore how the supramolecular net-suppressor can enhance therapy effectiveness by remodeling the tumor vascular-immune microenvironment in renal cancer.
  • Developed a supramolecular net-suppressor for cancer therapy.
  • Investigated its effects on tumor microenvironment dynamics.
  • Evaluated spatiotemporal synchronization of therapeutic agents.
  • The supramolecular net-suppressor significantly remodels the tumor microenvironment.
  • It enhances the effectiveness of anti-angiogenic agents and immune checkpoint inhibitors.
  • Observed improved coordination of immune and vascular responses in treatment.

Abstract

Advanced or metastatic renal cell carcinoma (RCC) responds poorly to current combination therapies, as anti-angiogenic agents and immune checkpoint inhibitors fail to act in a spatiotemporally synchronized manner. Consequently, their...

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Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/698828100fc35cd7a88473a5https://doi.org/10.1039/d5mh01936b
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