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Synapse
February 8, 2026Translational Vision Science & Technology0 citationsOpen Access

Anti–IL-6 Receptor Antibody Suppresses Visual Dysfunction in AQP4 Peptide-Immunized Mice

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YKYoshichika KatsuraYNYuko Nakatake-FuruieSOShinichi Onishi

Key Points

  • This research aims to determine the effectiveness of IL-6 receptor blockade in preventing visual impairment.
  • Utilized AQP4 peptide-immunized mice model.
  • Administered anti-IL-6 receptor antibody treatment.
  • Assessed visual function following treatment.
  • Demonstrated significant reduction in visual dysfunction in treated mice.
  • Highlighting the protective effects of IL-6 receptor blockade against visual impairment.

Abstract

IL-6 receptor blockade may be a viable strategy for preventing visual impairment in patients with NMOSD.

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Cite This Study

Katsura et al. (2026) studied this question.

synapsesocial.com/papers/698828210fc35cd7a8847631https://doi.org/10.1167/tvst.15.2.6
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