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February 8, 20260 citationsOpen Access

Sex disparities in ICU care and outcomes after cardiac arrest: a Swiss nationwide analysis

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SASimon A. AmacherUniversity Medical Center FreiburgTZTobias ZimmermannUniversity Hospital of BaselPGPimrapat GebertUniversity of Zurich

Key Points

  • This research aims to investigate differences in critical care and outcomes between sexes after cardiac arrest.
  • Analyzed adult patients admitted to Swiss ICUs from 2008 to 2022
  • Used nationwide prospective ICU registry data
  • Primary outcome focused on ICU mortality with secondary outcomes on admission probability and treatment provision.
  • Identified significant sex disparities in ICU mortality rates for cardiac arrest patients
  • Observed lower ICU admission rates and advanced treatment provision for women
  • Highlighted potential disadvantages for women, especially after out-of-hospital cardiac arrest.

Abstract

Background: Conflicting data exist regarding sex-specific outcomes after cardiac arrest. This study investigates sex disparities in the provision of critical care and outcomes of in-hospital (IHCA) and out-of-hospital cardiac arrest (OHCA) patients. Methods: Analysis of adult cardiac arrest patients admitted to certified Swiss intensive care units (ICUs) (01/2008-12/2022) using the nationwide prospective ICU registry. The primary outcome was ICU mortality, with secondary outcomes including ICU admission probability and advanced treatment provision. Conclusions: This study highlights sex disparities in short-term mortality and ICU resource allocation among cardiac arrest patients, with women potentially facing disadvantages, in particular after OHCA. The limitations of ICU registry data, particularly the lack of detailed cardiac arrest-specific and comorbidity information, restrict definitive conclusions. Future research should prioritize prospective studies with more granular data to better understand and address these disparities.

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Cite This Study

Amacher et al. (2025) studied this question.

synapsesocial.com/papers/698828850fc35cd7a8848177https://doi.org/10.5167/uzh-290911
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