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February 9, 2026Annals of Medicine and Surgery0 citationsOpen Access

Artificial light at night and melatonin suppression: an underrecognized neuroendocrine risk factor

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SBSyeda Tayyaba BatoolUAUmair AliMAMuhammad Abbas

Key Points

  • The aim is to investigate how artificial light at night affects melatonin secretion and its broader health implications.
  • Review of existing literature on artificial light exposure and melatonin disruptions.
  • Analysis of consequences on sleep, metabolism, and neuroendocrine functions.
  • Discussion of public health and clinical implications.
  • Chronic exposure to artificial light at night significantly suppresses melatonin production.
  • Melatonin suppression is associated with sleep disorders and metabolic dysregulation.
  • ALAN exposure may increase the risk of neuropsychiatric and cardiometabolic diseases.

Abstract

Artificial light at night (ALAN) has become an unavoidable feature of modern living, yet its biological consequences remain underestimated in clinical and public health discourse. Chronic exposure to nocturnal light disrupts melatonin secretion, alters circadian signaling, and interferes with neuroendocrine homeostasis. Emerging evidence links ALAN-induced melatonin suppression to sleep disorders, metabolic dysregulation, immune dysfunction, and increased risk of neuropsychiatric and cardiometabolic diseases. This Letter highlights ALAN as a modifiable environmental exposure with significant neuroendocrine implications and emphasizes the need for translational research and preventive strategies.

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Cite This Study

Batool et al. (2026) studied this question.

synapsesocial.com/papers/698979d9f0ec2af6756e7c71https://doi.org/10.1097/ms9.0000000000004779
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