This paper reframes reaction feasibility within the MID/QC substrate framework, showing that reactions occur only when transitional molecular configurations are coherence-viable. It introduces the concept of coherence corridors—geometric pathways that connect reactants and products through temporarily stable intermediates. The manuscript explains reaction suppression, catalytic enabling, and directional bias as consequences of substrate geometry rather than energetic thresholds. Reaction feasibility emerges as a geometric phenomenon governed by torsional alignment, decoherence pressure, and substrate constraints.
Chadwick Rasque (2026) studied this question.