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February 11, 20260 citations

Analysis of the pathological composition ratio of orbital space-occupying lesions in 7 515 cases: a single-center retrospective study.

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TZTianyi ZhouTZTe ZhangHYHuijing Ye

Key Points

  • This analysis aims to understand the types and prevalence of orbital space-occupying lesions in different age groups.
  • Conducted a retrospective review of 7515 cases of orbital lesions.
  • Categorized lesions based on their pathological composition.
  • Analyzed trends over the past two decades.
  • Inflammatory and vascular lesions dominate in younger patients.
  • Lymphoproliferative malignancies are more common in elderly patients.
  • A decline in vascular lesions was observed alongside a rise in malignant cases.

Abstract

The pathological spectrum of orbital space-occupying lesions in southern China is dominated by inflammatory and vascular lesions in younger patients and by lymphoproliferative malignancies in the elderly. Over the past two decades, vascular lesions have decreased, whereas lymphoproliferative and malignant lesions have become more prevalent, reflecting demographic aging and advances in diagnostic pathology. These findings provide updated epidemiologic evidence to guide the differential diagnosis and management of orbital tumours.

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Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/698c1bef267fb587c655e033https://doi.org/10.1016/j.jcjo.2026.01.019
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