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February 11, 2026JAAPA0 citations

PA- versus urologist-performed flexible cystoscopy

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JMJ. MisurkaMBMohamad B. BerjaouiKLKatherine Lajkosz

Key Points

  • The study aims to compare patient pain perceptions and bladder cancer detection rates between cystoscopy performed by PAs and urologists.
  • Secondary analysis of a single-center, prospective, double-blind, randomized controlled trial.
  • Involved 98 men undergoing flexible cystoscopy by either a PA or a SU.
  • Patients completed a pain questionnaire following the procedure.
  • Mean pain score for SU was 2.67 compared to 2.62 for PA (p = .92).
  • 23 cystoscopies had positive or suspicious findings (SU: 11 [23%]; PA: 12 [24%]).
  • Out of 15 samples taken, 8 were positive for urothelial cancer (SU: 3 [6.25%]; PA: 5 [10%]).

Abstract

ABSTRACT Introduction: We aimed to compare patient pain perceptions and bladder cancer detection rates following cystoscopy performed by physician associates/physician assistants (PAs) versus staff urologists (SUs). Methods: We performed a secondary analysis of our earlier single-center, prospective, double-blind, randomized controlled trial that originally investigated irrigation “bag squeeze” versus standard cystoscopy. In this analysis, 98 men who underwent flexible cystoscopy by either a SU or a PA were included. Patients completed a pain questionnaire following the procedure. Results: The mean pain score for SU-performed cystoscopy was 2.67 compared with 2.62 for PA-performed cystoscopy ( p = .92). A total of 23 cystoscopies (SU-performed, 11 23%; PA-performed, 12 24%; p > .05) resulted in positive or suspicious findings. Pathologic sampling was performed for 15 (SU-performed, 6; PA-performed, 9), out of which 8 total (SU-performed, 3 6.25%; PA-performed 5 10%) were positive for urothelial cancer. Conclusions: PA-performed cystoscopies demonstrate similar outcomes to those performed by physicians in terms of patient-reported pain scores and malignancy detection rates.

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Cite This Study

Misurka et al. (2026) studied this question.

synapsesocial.com/papers/698c1cd3267fb587c655f827https://doi.org/10.1097/01.jaa.0000000000000323
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