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February 12, 2026Current Hypertension Reviews0 citations

Nonadherence, Clinic Inertia, and Ineffective Adherence in Antihypertensive Treatment in Latin America

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ALA S Luís

Key Result

Nonadherence to antihypertensive treatment, with rates ranging from 14% to 94%, and clinical inertia drive poorly controlled hypertension and ineffective adherence in Latin America.

Key Points

  • This review focuses on the challenges of nonadherence and clinical inertia in managing hypertension in Latin America.
  • Review of literature on nonadherence and clinical inertia
  • Analysis of hypertension control rates
  • Examination of socioeconomic impacts and potential interventions
  • Nonadherence rates in Latin America range from 14% to 94%
  • Clinical inertia complicates treatment escalation
  • Ineffective adherence affects many patients despite following treatments

Structured PICO

P
Population
Patients with arterial hypertension in Latin America
I
Intervention
Comprehensive strategies including patient-centered interventions, provider education, healthcare reforms, and team-based care

Comprehensive strategies, including patient-centered interventions and team-based care, are needed to address the high rates of nonadherence and clinical inertia in hypertension management in Latin America.

Abstract

Arterial hypertension (HTN) is the leading modifiable risk factor for cardiovascular diseases in Latin America; however, control rates remain inadequate. Two primary contributors to this public health crisis are nonadherence to antihypertensive treatment and clinical inertia. Non-adherence rates in the region range from 14% to 94%, while clinical inertia, defined as healthcare providers' failure to escalate or modify treatment, when necessary, further complicates the issue. The interplay between these two factors creates a self-perpetuating cycle that leads to poorly controlled hypertension, increased morbidity and mortality, and a greater economic burden. A primary concern is "ineffective adherence", which occurs when patients follow prescribed treatments but do not achieve desired outcomes. This phenomenon is primarily driven by medical inertia and affects a significant proportion of cases. This review examines the scope of these issues in Latin America, their socioeconomic impacts, and potential interventions to mitigate their effects. To better manage hypertension, comprehensive strategies are recommended, including patient-centered interventions, education directed at providers, essential healthcare reforms, and team-based care strategies that involve non-physician providers.

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Cite This Study

A S Luís (2026) conducted a review in Arterial hypertension. Antihypertensive treatment was evaluated. Nonadherence to antihypertensive treatment, with rates ranging from 14% to 94%, and clinical inertia drive poorly controlled hypertension and ineffective adherence in Latin America.

synapsesocial.com/papers/698d6e7b5be6419ac0d54495https://doi.org/10.2174/0115734021393935251103110508
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