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February 12, 2026Chemical Communications0 citationsOpen Access

Differential self-assembly of sequence-isomeric phosphoestamers

JWJames WilliamsonTPTomasz K. PiskorzBCBini Claringbold

Key Points

  • This research aims to understand how the sequence in phosphoestamers affects their self-assembly behavior.
  • Used NMR to analyze structural characteristics of phosphoestamers
  • Employed molecular dynamics simulations to assess self-assembly dynamics
  • Studied tetrameric forms of phosphoestamers
  • Identified distinct self-assembly patterns based on sequence variations
  • Demonstrated the importance of sequence in influencing structural behavior
  • Provided insights into larger sequence-structure relationships in biomolecules

Abstract

NMR and molecular dynamics have been used to study the relationship between sequence and self-assembly in tetrameric phosphoestamers, providing a useful model for understanding larger sequence/structure relationships.

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Cite This Study

Williamson et al. (2026) studied this question.

synapsesocial.com/papers/698d6eca5be6419ac0d54a1ehttps://doi.org/10.1039/d5cc06986f
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