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February 14, 2026AIP Advances0 citationsOpen Access

High-Tc SQUID-based ultra-low field MRI in unshielded environments

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SLShu LiaoHHH. Huang

Key Points

  • This work aims to develop a high-performance MRI technique utilizing high-Tc SQUIDs in ultra-low magnetic fields.
  • Optimized NMR/MRI techniques applied to water phantoms and human fingers
  • Assessment of image contrast and spatial resolution under unshielded conditions
  • Experimentation conducted at magnetic fields of 98 μT
  • Achieved a signal-to-noise ratio of 62 for a 200 μL water column
  • Demonstrated a spatial resolution of 2 mm, comparable to existing ULF MRI systems
  • First clear images of fingers using high-Tc SQUIDs were obtained, highlighting potential for clinical use.

Abstract

A high-performance MRI based on high-Tc SQUID and flux coupling at ultralow magnetic fields is reported in this work. The technique of NMR/MRI was optimized to study MRI of water phantoms and fingers. An SNR of 62 in image contrast was achieved for a water column of 200 μL at magnetic fields of 98 μT. The MRI showed high image contrast and demonstrated a spatial resolution of 2 mm for samples in magnetically unshielded environments. This resolution is comparable to the current state-of-the-art values (typically 2.0–3.0 mm) reported for SQUID-based ULF MRI systems. A clear image of fingers was demonstrated for the first time using high-Tc SQUIDs, which shows promise for biological or clinical applications.

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Cite This Study

Liao et al. (2026) studied this question.

synapsesocial.com/papers/699011812ccff479cfe582edhttps://doi.org/10.1063/9.0001031
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