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February 16, 2026RSC Medicinal Chemistry0 citations

A Medicinal Chemistry Perspective on SIRT3 Modulators in Disease Treatment

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YLYaoLiang LiYBYuqi BaoCYCui Yunxia

Key Points

  • To explore the role of SIRT3 modulators in disease treatment from a medicinal chemistry perspective.
  • Review of existing literature on SIRT3
  • Analysis of SIRT3's biological functions
  • Discussion of therapeutic implications of SIRT3 modulation
  • SIRT3 is vital for cellular energy metabolism and oxidative stress response
  • Modulation of SIRT3 shows potential in disease treatment
  • Understanding SIRT3's role can lead to novel therapeutic strategies

Abstract

As the primary mitochondrial deacetylase, SIRT3 plays a central role in key biological processes such as cellular energy metabolism, oxidative stress response, and apoptosis regulation. It is also closely associated...

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/69926503eb1f82dc367a0e91https://doi.org/10.1039/d5md01007a
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