Background Swine influenza virus (SIV) is endemic in China, threatening the swine industry and public health. This meta‐analysis estimated the national pooled prevalence of SIV (2010–2025) and identified key sources of heterogeneity. Methods Following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines, six databases were searched, yielding 73 eligible studies with 411,930 samples. A random‐effects model pooled prevalence estimates, and subgroup analyses explored heterogeneity. Results The pooled SIV prevalence was 30.3% (95% confidence interval CI: 24.5%–36.4%) with extreme heterogeneity ( I 2 = 100%, p H3). Sensitivity analysis confirmed robustness, but publication bias (Egger’s test, p = 0.0009) suggests potential overestimation. Conclusion SIV is widespread in China but exhibits marked spatiotemporal and methodological variability. A single national prevalence figure is insufficient for risk assessment. Surveillance and control strategies must be targeted and context‐specific. This study provides a critical, albeit potentially overestimated, epidemiological baseline for evidence‐based interventions.
Yang et al. (2026) studied this question.