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February 16, 2026International Journal of Gynecology & Obstetrics0 citations

Severe adverse cardiac events in pregnant women with congenital heart disease at a university hospital in southern Thailand

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KPKrantarat PeeyananjarassriCSChitkasaem SuwanrathKWKanjarut Wongwaitaweewong

Key Points

  • This study evaluates the incidence and characteristics of severe adverse cardiac events in pregnant women with congenital heart disease.
  • Retrospective review of medical records of pregnant women with congenital heart disease at Songklanagarind Hospital.
  • Data collected included clinical and cardiac characteristics, severe adverse cardiac events, and obstetric complications.
  • Excluded pregnancies with invalid diagnoses or missing data.
  • SCEs occurred in 24.7% of pregnancies, including six maternal deaths (1.7%).
  • Most common event was deterioration of functional class by ≥2 levels.
  • 87.1% of SCEs were deemed preventable, related to both patients and healthcare providers.

Abstract

Abstract Objective This study aimed to evaluate the incidence and characteristics of severe adverse cardiac events (SCEs) in pregnant women with congenital heart disease (CHD), and to determine the proportion and contributing factors of preventable events. Methods We retrospectively reviewed the medical records of pregnant women with CHD who delivered at Songklanagarind Hospital between January 1, 2006, and December 31, 2024. Pregnancies with an invalid diagnosis, missing essential data, or loss to follow‐up before delivery or termination were excluded. Collected data included baseline clinical and cardiac characteristics, SCEs, obstetric complications, and factors contributing to preventable failures. Results During the 19‐year period, SCEs occurred in 24.7% (85 of 344) of pregnancies, including six maternal deaths (1.7%). The most common event was deterioration of New York Heart Association functional class by ≥2 levels, followed by congestive heart failure. Most cases (87.1%, 74 of 85) were considered preventable, with contributing factors related to both patients and healthcare providers. Conclusion The incidence of SCEs in pregnancies with CHD was high, with the majority deemed preventable.

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Cite This Study

Peeyananjarassri et al. (2026) studied this question.

synapsesocial.com/papers/69926552eb1f82dc367a1354https://doi.org/10.1002/ijgo.70859
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