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February 19, 2026American journal of optometry and archives of American Academy of Optometry0 citations

Steady State Distribution of Oxygen and Carbon Dioxide in the in Vivo Cornea of an Eye Covered by a Gas‐permeable Contact Lens

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IFI FattMBMarie BieberSPStephen D. Pye

Key Points

  • This study aims to analyze the distribution of oxygen and carbon dioxide in the cornea under a gas-permeable contact lens.
  • Calculated oxygen and carbon dioxide profiles for open and closed eyes with a contact lens.
  • Evaluated the thickness and oxygen transmissibility of the gas permeable polymer.
  • Assessed changes in oxygen flux across the anterior and posterior surfaces of the cornea.
  • Gas permeable lenses significantly improve oxygen transmissibility compared to nonpermeable materials.
  • Oxygen flux across the anterior surface is reduced by the lens while maintaining total oxygen supply to the cornea.
  • The posterior surface demonstrates an increased oxygen flux, contributing to corneal health.

Abstract

ABSTRACT Oxygen and carbon dioxide profiles were calculated for the open and closed eye covered with a contact lens made of gas permeable polymer. The results show the thickness and oxygen transmissibility required of the oxygen permeable polymer to make it a significant improvement over nonpermeable contact lens materials. The results also show how the oxygen flux across the anterior surface is decreased by the lens, and how the flux from the posterior surface increases thereby maintaining an almost constant total oxygen flux to the cornea.

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Cite This Study

Fatt et al. (1969) studied this question.

synapsesocial.com/papers/6996a77aecb39a600b3ed359https://doi.org/10.1002/j.2330-9474.1969.tb03628.x
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