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February 19, 2026Diabetes Technology & Therapeutics0 citations

Accuracy of Real-Time Continuous Glucose Monitoring System in Hospitalized Patients with Diabetes and Chronic Kidney Disease

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YKYoshinori KakutaniTMTomoaki MoriokaSMShoko Miyamoto

Key Points

  • This study aims to evaluate the accuracy of real-time continuous glucose monitoring in hospitalized patients with diabetes and chronic kidney disease.
  • Conducted a prospective observational study with 52 diabetes patients excluding those with acute kidney conditions.
  • Categorized participants by estimated glomerular filtration rate into groups G1-2, G3, and G4-5.
  • Measured capillary glucose using a validated point-of-care device alongside CGM readings.
  • Assessed accuracy using mean absolute relative difference (MARD), correlation analyses, and Bland–Altman plots.
  • Analyzed 1603 paired glucose values with a strong correlation (r = 0.91, P < 0.001) between CGM and point-of-care readings.
  • Overall mean absolute relative difference (MARD) was 17.0%; group-specific values reported as 19.4% in G1/2, 15.5% in G3, and 13.5% in G4/5 (P < 0.001).
  • CEG analyses indicated high agreement, with over 99% of values in clinically acceptable zones.

Abstract

Objective: Real-time continuous glucose monitoring (CGM) systems are beneficial for patients with diabetes by providing a comprehensive assessment of glycemic status and reducing hypoglycemia. However, their performance in patients with both diabetes and chronic kidney disease (CKD) during hospitalization remains unclear. This study aimed to evaluate the accuracy of real-time CGM in hospitalized patients with diabetes and CKD. Research Design and Methods: We conducted a prospective observational study including 52 patients with diabetes after excluding those with acute kidney injury, active glomerulonephritis, requiring intensive care, or undergoing hemodialysis. Participants were categorized by estimated glomerular filtration rate (eGFR, mL/min/1.73 m 2 ) into G1-2 (≥60), G3 (30–59), and G4-5 (99% of values within clinically acceptable zones. Conclusions: The Dexcom G6 demonstrated reliable accuracy in hospitalized patients with diabetes and CKD, with better performance in advanced CKD. These findings support its clinical utility in this population.

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Cite This Study

Kakutani et al. (2026) studied this question.

synapsesocial.com/papers/6996a7ffecb39a600b3ee432https://doi.org/10.1177/15209156261423902
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