Vector Flow Mapping-derived IVPD recoil was significantly reduced to 1.0 mmHg in patients with ischemic heart disease and left ventricular aneurysm compared to 2.5 mmHg in patients without aneurysm, indicating impaired apical suction (P < 0.01).
Observational (n=37)
No
Does vector flow mapping (VFM) accurately assess impaired apical suction and intraventricular pressure differences in patients with ischemic heart disease and left ventricular aneurysm compared to invasive measurements?
Vector flow mapping is a feasible noninvasive tool to identify the loss of apical suction and impaired left atrial-left ventricular driving force in patients with post-infarction left ventricular aneurysm.
Effect estimate: P-value <0.01
Absolute Event Rate: 1% vs 2.5%
p-value: p=<0.01
Abstract Hemodynamic force (HDF) analysis using vector flow mapping (VFM) enables noninvasive assessment of intraventricular pressure differences (IVPDs). In this study, we evaluated the apical suction from late systole to early diastole in patients with ischemic heart disease (IHD) with or without left ventricular aneurysm (LVA), validated against simultaneous left atrial–LV pressure measurements. A total of 37 participants were evaluated: 11 healthy controls, 11 patients with IHD without LVA, and 15 with LVA. VFM-derived IVPDs were quantified as IVPD recoil (late systole) or IVPD RF (early diastole). Patients with LVA showed markedly reduced IVPD recoil and the combined parameter (IVPD VFM recoil + RF) compared with those with IHD, indicating impaired apical suction. IVPD RF and the combined parameter (IVPD VFM recoil + RF) correlated with transmitral E-wave ( r = 0.54, P < 0.01 and r = 0.45, P = 0.03); the combined parameter (IVPD VFM recoil + RF) showed significant correlation with catheter-derived simultaneous pressure differences ( r = 0.40, P < 0.05). These findings demonstrate that VFM identifies loss of apical suction in LVA and reflects impaired LA–LV driving force. VFM offers a practical noninvasive tool for evaluating diastolic suction beyond Doppler indices and may improve physiological assessment in post-infarction LV remodeling.
Sugiyama et al. (2026) conducted an observational in Patients with ischemic heart disease with or without left ventricular aneurysm and healthy controls (n=37). Vector Flow Mapping (VFM)-derived Intraventricular Pressure Difference (IVPD) analysis vs. Patients with ischemic heart disease without left ventricular aneurysm (IHD group) and healthy controls was evaluated on IVPD VFM recoil (late systole intraventricular pressure difference reflecting apical suction) and combined IVPD VFM recoil + RF (sum of late systolic recoil and early diastolic rapid filling pressure difference) (P-value <0.01, p=<0.01). Vector Flow Mapping-derived IVPD recoil was significantly reduced to 1.0 mmHg in patients with ischemic heart disease and left ventricular aneurysm compared to 2.5 mmHg in patients without aneurysm, indicating impaired apical suction (P < 0.01).