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February 19, 2026Reaction Chemistry & Engineering0 citations

Efficient Synthesis of Ortho- or Para-aminophenol via Diazo Coupling Reduction Process and Scalable Manufacturing Chlorzoxazone

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SLShiyun LiWCWenxin ChenACAo Chen

Key Points

  • The aim is to develop an efficient synthesis method for ortho- or para-aminophenol using a diazo coupling reduction process.
  • Utilization of a diazo coupling reduction process for synthesizing aminophenol.
  • Focus on avoiding harsh reaction conditions and expensive noble metal catalysts.
  • Scalable manufacturing techniques for chlorzoxazone production.
  • The developed method provides a safer and cost-effective approach to synthesize aminophenol.
  • Demonstrated scalability that can be applied in industrial settings.

Abstract

Aminophenol are versatile intermediates widely utilized in the pharmaceutical, dye and pigment, and materials science industries. Conventional synthetic methods typically involve harsh reaction conditions, use expensive noble metal catalysts, or...

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Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6996a84cecb39a600b3eed18https://doi.org/10.1039/d5re00503e
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