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February 19, 2026Future Science OA1 citationsOpen Access

Soluble cytokine receptor levels in obstructive sleep apnea patients treated with continuous positive airway pressure therapy

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SHSarahRose HallLFLisa A. FreeburgSKSamira Khan

Key Points

  • To examine the relationship between soluble cytokine receptor levels and therapeutic response in patients with obstructive sleep apnea (OSA) treated with CPAP.
  • Measured levels of soluble cytokine receptors in OSA patients.
  • Assessed the potential correlation with CPAP therapy response.
  • Included specific receptors like sCD30, sEGFR, sIL1RII, and sVEGFR2.
  • Identified sCD30, sEGFR, sIL1RII, and sVEGFR2 as potential biomarkers of cytokine activation.
  • Indicated these receptors may reflect the therapeutic response to CPAP in patients with OSA.

Abstract

These results identified that a specific set of soluble cytokine receptors, including sCD30, sEGFR, sIL1RII, and sVEGFR2, may serve as indices of cytokine activation in patients with OSA and also identify therapeutic response such as CPAP.

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Cite This Study

Hall et al. (2026) studied this question.

synapsesocial.com/papers/6996a84cecb39a600b3eed9bhttps://doi.org/10.1080/20565623.2025.2553471
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Biomarkers of Sleep Apnea2012 · 100 citations
  2. 2Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis2019 · 4,255 citations
  3. 3Relationships between Obstructive Sleep Apnea Syndrome, Continuous Positive Airway Pressure Treatment, and Inflammatory Cytokines2014 · 25 citations
  4. 4Effects of nasal CPAP on exhaled SIRT1 and tumor necrosis factor-α in patients with obstructive sleep apnea2016 · 19 citations
  5. 5Long-Term Effect of Continuous Positive Airway Pressure Therapy on Inflammation Markers of Patients with Obstructive Sleep Apnea Syndrome2009 · 146 citations