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February 19, 2026RSC Advances0 citationsOpen Access

N -Substitution effects on the conformations of iminosugar analogues of 1-deoxy- l -idose and 1-deoxy- l -iduronic acid

LTLorenzo TagliettiEPEva PalombaHLHeiko Lange

Key Points

  • To investigate how N-substitution influences the conformations of iminosugar analogues derived from l-idose and l-iduronic acid.
  • Synthesis of a library of iminosugar analogues
  • Conducting a complete conformational analysis
  • Detailed insights into the impact of N-substitution on ring dynamics
  • Identification of distinct conformational behaviors in synthesized analogues

Abstract

We herein report the synthesis and complete conformational analysis of a focused library of iminosugar analogues of l -idose and l -iduronic acid designed to probe the impact of N -substitution on ring dynamics.

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Cite This Study

Taglietti et al. (2026) studied this question.

synapsesocial.com/papers/6996a957ecb39a600b3f04cbhttps://doi.org/10.1039/d5ra09936f
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