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February 21, 2026Brain and Spine0 citationsOpen Access

Hybrid Operating Rooms for the Treatment of Complex Middle Cerebral Artery Aneurysms: A Technical Note.

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DTDieter ThijsAntwerp University HospitalARAna Lilia Villagrana RodríguezHospital Universitari Germans Trias i PujolTMTomas Menovsky

Key Points

  • This research aims to outline the technical application of a hybrid approach for treating complex middle cerebral artery aneurysms.
  • Technical report on three cases involving large, distal, and fusiform MCA aneurysms.
  • Utilization of microcatheter-guided flash fluorescence for revascularization.
  • Endovascular parent vessel occlusion after verifying bypass patency with intraoperative angiography.
  • Successful implementation of the hybrid flash-fluorescence technique for vessel identification in all three cases.
  • Reduction in surgical risks and operative time compared to traditional methods.
  • Facilitation of complex aneurysm treatments without large craniotomy or significant dissection.

Abstract

The recent emergence of hybrid operating rooms (H-OR) broadens treatment options for complex intracranial aneurysms. Combining endovascular options enabled by the H-OR with refined microsurgical techniques could provide less arduous treatment alternatives for large, distal, and fusiform MCA aneurysms. To describe the technical nuances of a hybrid treatment consisting of microcatheter-guided flash fluorescence to enable revascularization bypass and endovascular parent vessel occlusion (PVO) in three different cases of large, distal and fusiform MCA aneurysms. A technical report of three cases is provided. At a H-OR, after STA harvest and side-appropriate craniotomy, femoral artery access was obtained and a microcatheter was guided in the corresponding aneurysm. Indocyanine green (ICG) was injected throughout the microcatheter while running a videoangiography on the surgical microscope, allowing straight-forward identification of the appropriate vessel recipient for the revascularization bypass. The described hybrid flash-fluorescence technique allowed straight-forward identification of the appropriate vessel recipient for the revascularization bypass in all three cases. After completion of the bypass and verification of its patency by intraoperative angiography, the aneurysms and their parent vessels were occluded endovascularly. This hybrid treatment using modern endovascular and microsurgical techniques obviates the need for a large craniotomy, Sylvian fissure dissection and aneurysm manipulation, while reducing surgical risks and operative time in the treatment of complex fusiform MCA aneurysms. The H-OR room can result in new proficient, creative and safe treatment options of different neurovascular pathologies • Hybrid operating rooms broaden treatment options for complex intracranial aneurysms • Microcatheter-guided flash fluorescence enabled easier revascularization bypass • Combined with endovascular, provided new alternatives for fusiform MCA aneurysms • Further availability of hybrid operating rooms may enable new creative treatments

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Cite This Study

Thijs et al. (2026) studied this question.

synapsesocial.com/papers/69994a7f873532290d01ef47https://doi.org/10.1016/j.bas.2026.105934
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