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February 21, 2026Yonago acta medica0 citationsOpen Access

Longitudinal Dynamics of Soluble NKG2D Ligands in Mild and Moderate Coronavirus Disease-2019

KNKyosuke NagamizuYNYukari NishikawaMTMiyako Takata

Key Points

  • This research aims to investigate the changes in soluble NKG2D ligands over time and their connections to clinical factors during COVID-19.
  • Longitudinal analysis from acute phase to hospital discharge
  • Measurement of soluble NKG2D ligand levels
  • Correlation with clinical parameters
  • Changes in soluble NKG2D ligands observed throughout the course of COVID-19
  • Relationships identified between ligand levels and clinical severity
  • Potential markers for predicting disease outcomes suggested

Abstract

Background The soluble form of NKG2D (sNKG2D) ligands has been implicated in the severity of coronavirus disease-2019 (COVID-19). However, their longitudinal dynamics from the acute phase to hospital discharge and their relationships with clinical parameters are unclear. This study aimed to investigate the longitudinal dynamics of these ligands and determine their relationship with clinical parameters.

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Cite This Study

Nagamizu et al. (2026) studied this question.

synapsesocial.com/papers/69994ba9873532290d01fd3fhttps://doi.org/10.33160/yam.2026.02.015
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