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February 22, 2026Neuroimage Reports0 citationsOpen Access

Corticomuscular coherence and its non-invasive modulation in stroke applications: a narrative review

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YXYuchen XuSZShaomin ZhangMWMinmin Wang

Key Points

  • This review aims to explore corticomuscular coherence and its modulation for enhancing recovery after stroke.
  • Reviewed literature on the origins of corticomuscular coherence in movement execution.
  • Analyzed how strokes disrupt normal corticomuscular coherence patterns.
  • Summarized potential non-invasive neuromodulation strategies for rehabilitation.
  • Corticomuscular coherence patterns are significantly altered in stroke patients.
  • Non-invasive modulation techniques show promise in restoring normal CMC patterns.
  • A better understanding of beta band activity contributes to improved stroke rehabilitation approaches.

Abstract

Neural activities are widely observed in the central nervous system and are essential for movement execution. Corticomuscular coherence (CMC) represents the coherence of oscillatory communication between motor cortex and peripheral muscles. Motor function impairments caused by stroke often involve abnormal CMC patterns. This review aimed to investigate CMC and how to modulate them for post-stroke functional recovery. We first introduced the origins of CMC in movement execution. We then explored how stroke affects CMC. Based on these abnormal CMC patterns, we summarized potential non-invasive neuromodulation strategies. A deeper understanding of CMC in beta band (∼15-30 Hz) could clarify the physiological mechanisms underlying movement and aid in improving stroke rehabilitation.

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Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/699a9cc6482488d673cd284ehttps://doi.org/10.1016/j.ynirp.2026.100329
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