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February 22, 2026Cell Reports Medicine0 citationsOpen Access

Neuronal PPP2R5C in plasma is a potential biomarker for early diagnosis of Alzheimer’s disease

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SLShilin LuoHLHui LiuTXTingting Xiao

Key Points

  • The aim is to evaluate the role of neuronal PPP2R5C in plasma as an early biomarker for Alzheimer’s disease.
  • Analysis of plasma levels of PPP2R5C in individuals with early-stage Alzheimer's disease.
  • Comparative evaluation with control subjects.
  • Statistical correlation of PPP2R5C levels with cognitive decline indicators.
  • Higher levels of PPP2R5C were detected in participants with early Alzheimer's compared to controls.
  • The presence of PPP2R5C correlated significantly with cognitive impairment scores.
  • Identifying PPP2R5C as a potential early diagnostic marker for Alzheimer's disease.

Abstract

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Cite This Study

Luo et al. (2026) studied this question. Neuronal PPP2R5C detected in plasma shows potential as a biomarker for early diagnosis of Alzheimer's disease.

synapsesocial.com/papers/699a9ceb482488d673cd296ahttps://doi.org/10.1016/j.xcrm.2026.102631
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