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February 22, 2026African journal of reproduction and gynaecological endoscopy0 citationsOpen Access

Mock Embryo Transfer vs. Hysteroscopy-Assisted Mock Embryo Transfer: Which has a Better Predictive Value? A Retrospective Cohort Study

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EOElijah N. OnwudiweCOChinyere Florence OnwudiweLULotanna Umeano

Key Points

  • The aim is to compare the predictive value and outcomes of mock embryo transfer versus hysteroscopy-assisted mock embryo transfer.
  • Retrospective cohort study design at a single fertility clinic
  • Involved 151 participants grouped into mock embryo transfer and hysteroscopy-assisted groups
  • Evaluated outcomes included ease of embryo transfer, clinical pregnancy rates, live birth rates, and miscarriage rates
  • Data analysis conducted for significant differences between the two techniques
  • No statistically significant difference in ease of embryo transfer (p = 0.384)
  • Clinical pregnancy rates were 46.7% for mock embryo transfer and 55.3% for hysteroscopy-assisted (p = 0.291)
  • Live birth rates were 38.7% for mock embryo transfer and 32.9% for hysteroscopy-assisted (p = 0.459)
  • Miscarriage rates were 6.7% for mock embryo transfer compared to 15.8% for hysteroscopy-assisted (p = 0.149)

Abstract

Abstract Objective: This study compares the predictive value of mock embryo transfer (MET) and hysteroscopy-assisted mock embryo transfer (HA-MET). Materials and Methods: This is a single-center retrospective cohort study conducted between November 2022 and 2025, involving 151 participants at Pink Petals Fertility Clinic, Enugu, Nigeria, who were grouped into MET and HA-MET. The primary outcome was ease of embryo transfer/Difficult (ETs), the secondary outcome measures were positive pregnancy test, live birth rate, and miscarriage. Results: A total of 151 patients were analyzed (Mock ET = 75, hysteroscopy-assisted ET =76). There was no statistically significant difference in ease of ET between groups ( p = 0.384). Clinical pregnancy rates were 46.7% for Mock ET and 55.3% for hysteroscopy-assisted ET ( p = 0.291), while live birth rates were 38.7% and 32.9%, respectively ( p = 0.459), and miscarriage rates (6.7% vs. 15.8%, p = 0.149) also showed no significant differences. Conclusion: Hysteroscopy-assisted embryo transfer did not confer a significant advantage over conventional MET in terms of ease of transfer, clinical pregnancy, live birth, or miscarriage outcomes. Conventional mock ET remains an effective approach, while hysteroscopy should be reserved for selected patients with suspected intrauterine abnormalities.

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Cite This Study

Onwudiwe et al. (2026) studied this question.

synapsesocial.com/papers/699a9d50482488d673cd3181https://doi.org/10.4103/ajrge.ajrge_9_25
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