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February 23, 2026Archives of Endocrinology and Metabolism1 citationsOpen Access

The decline of iodine therapy in the treatment of Graves’ disease in a hospital center: a 20-year analysis

ISIsabela Busto SilvaGCGisah Amaral de CarvalhoFMFabíola Yukiko Miasaki

Key Points

  • To analyze trends in the use of iodine therapy for treating Graves' disease over a 20-year period.
  • Reviewed treatment records for Graves’ disease over two decades
  • Analyzed the frequency of radioiodine therapy as first-line and salvage treatments
  • Evaluated the effectiveness and safety of radioiodine therapy
  • Notable decline in radioiodine therapy usage as a primary treatment
  • Radioiodine therapy maintained effectiveness and safety
  • Successful cure rates remained high despite reduced usage

Abstract

Significant changes were observed in GD treatment, with a decline in the use of RAI as a first-line or salvage therapy. Nonetheless, radioiodine therapy remained an effective and safe treatment modality with successful cure rates.

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Cite This Study

Silva et al. (2026) studied this question.

synapsesocial.com/papers/699bee1c1c6c6bad5397fd7chttps://doi.org/10.20945/2359-4292-2026-0013
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