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October 24, 2023Journal of the American College of Cardiology191 citationsOpen Access

The Mortality Burden of Untreated Aortic Stenosis

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PGPhilippe GénéreuxRSRahul SharmaRCRobert J. Cubeddu

Key Points

  • To assess the mortality risk associated with untreated aortic stenosis across varying severity levels.
  • Analyzed mortality risk levels for untreated aortic stenosis severity

Structured PICO

P
Population
Patients with untreated aortic stenosis (AS) across all levels of severity
O
Outcome
Mortality riskhard clinical

Untreated aortic stenosis carries a high mortality risk across all severity levels, highlighting the need to address low rates of aortic valve replacement in severe cases.

Abstract

Patients with AS have high mortality risk across all levels of untreated AS severity. Aortic valve replacement rates remain low for patients with severe AS, suggesting that more research is needed to understand barriers to diagnosis and appropriate approach and timing for aortic valve replacement.

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Cite This Study

Généreux et al. (2023) studied this question.

synapsesocial.com/papers/699c76baae31d3388c0cbd72https://doi.org/10.1016/j.jacc.2023.09.796
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prospective Study of Asymptomatic Valvular Aortic Stenosis1997 · 1,149 citations
  2. 2Heart Disease and Stroke Statistics—2023 Update: A Report From the American Heart Association2023 · 6,114 citations
  3. 3Impact of Moderate Aortic Stenosis in Patients With Heart Failure With Reduced Ejection Fraction2023 · 32 citations
  4. 4Trends in Utilization of Aortic Valve Replacement for Severe Aortic Stenosis2022 · 91 citations
  5. 5Outcomes of Patients With Discordant High-Gradient Aortic Valve Stenosis2020 · 14 citations