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February 25, 2026JAMA Network Open2 citationsOpen Access

Rate of Pharmacotherapy for Tobacco Smoking Cessation in Patients With New Peripheral Artery Disease

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KCK. Roger CohenMJMegan S. JarvisOAOmid Ameli

Key Points

  • This study aims to explore how often patients with newly diagnosed peripheral artery disease use varenicline for quitting smoking.
  • Conducted a cross-sectional analysis using US insurance claims data
  • Focused on adults with newly diagnosed peripheral artery disease
  • Assessed the rate of varenicline prescriptions for smoking cessation
  • Identified the percentage of patients using varenicline for smoking cessation
  • Showed a potential gap in pharmacotherapy rates among patients
  • Highlighted variability in treatment adherence in the target population

Abstract

This cross-sectional study uses US insurance claims data to examine the rate of varenicline use for tobacco smoking cessation among adults with newly diagnosed peripheral artery disease.

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Cite This Study

Cohen et al. (2026) studied this question.

synapsesocial.com/papers/699e90eff5123be5ed04e1bdhttps://doi.org/10.1001/jamanetworkopen.2025.58244
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cessation of Smoking in Patients with Intermittent Claudication1987 · 310 citations
  2. 2Effectiveness of a Smoking Cessation Program for Peripheral Artery Disease Patients2010 · 137 citations
  3. 3Neuropsychiatric safety and efficacy of varenicline, bupropion, and nicotine patch in smokers with and without psychiatric disorders (EAGLES): a double-blind, randomised, placebo-controlled clinical trial2016 · 1,186 citations
  4. 4Prescription Smoking-Cessation Medication Fills and Spending, 2009–20192022 · 1 citations
  5. 5A modern day perspective on smoking in peripheral artery disease2023 · 36 citations