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February 25, 2026Pediatric Radiology6 citationsOpen Access

Artificial intelligence in paediatric neuroradiology: current landscape, challenges, and future directions

BKBrendan S. KellySCSimon M. CliffordKMKshitij Mankad

Key Points

  • This review aims to evaluate the integration of artificial intelligence in paediatric neuroradiology and identify barriers to its adoption.
  • Conducted a narrative review of peer-reviewed studies from the past decade.
  • Focused on AI applications like image segmentation, lesion detection, and decision support.
  • Evaluated unique paediatric considerations, including brain development and data scarcity.
  • AI techniques, particularly deep learning, showed success in tumour segmentation and lesion detection.
  • Despite advancements, limited clinical adoption due to implementation costs and data issues.
  • Identified the need for data-sharing initiatives and revised ethical frameworks for better integration.

Abstract

This narrative review maps the current landscape of artificial intelligence (AI) in paediatric and fetal neuroradiology, critically evaluating current practice, barriers to clinical adoption, and future potential. We searched for peer-reviewed studies from the last decade, focusing on image segmentation, lesion detection, classification, prognostication, and clinical decision support in paediatric brain imaging. Particular consideration was given to unique paediatric factors such as brain development and data scarcity. AI techniques, notably deep learning, have demonstrated success in automated brain tumour segmentation, detection of epileptogenic lesions, and radiomics-based classifiers predicting tumour histology and molecular subtypes. Despite these advancements, clinical adoption remains limited. Key barriers identified include high implementation costs, limited large-scale diverse paediatric datasets, and concerns regarding safety, bias, and regulatory approval. Addressing these issues through data-sharing initiatives, federated learning, paediatric-specific validation, and revised ethical and regulatory frameworks is crucial. Ongoing multi-institutional collaborations can facilitate AI's integration into paediatric neuroradiology, complementing radiologists and improving paediatric care.

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Cite This Study

Kelly et al. (2026) studied this question.

synapsesocial.com/papers/699e91b2f5123be5ed04f5c6https://doi.org/10.1007/s00247-026-06547-9
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