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February 26, 20260 citations

Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review.

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KSKatarzyna SkierbiszewskaBTBERNARD TUREKTJT. Jasinski

Key Points

  • To evaluate the effectiveness of synthetic bone substitutes in equine veterinary medicine.
  • Systematic review of various synthetic bone substitutes
  • Assessment of their osteoconductive and osteoinductive properties
  • Consideration of biologically active additives like autologous bone marrow
  • Hydroxyapatite and calcium phosphate demonstrated favorable outcomes for bone healing
  • The addition of autologous bone marrow improved osteogenic and chondrogenic effects
  • Segmental bone defect treatments require careful consideration of weight-bearing limitations

Abstract

In equine medicine, hydroxyapatite, calcium phosphate and β-tricalcium phosphate were the leading alloplastics applied. When applied alone, they demonstrated osteoconductive and osteoinductive properties, while the addition of biologically active additives-especially autologous bone marrow-enhanced these biological properties toward osteogenic and chondrogenic effects. Treatment outcomes were generally favourable, although segmental bone defect treatment requires considering the limitations associated with weight-bearing effects. These findings suggest alloplastics in horses may be particularly beneficial for treating certain bone diseases.

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Cite This Study

Skierbiszewska et al. (2026) studied this question.

synapsesocial.com/papers/699f956d1bc9fecf3dab3180https://doi.org/10.1002/evj.70151
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