PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 26, 2026Russian Journal of General Chemistry0 citations

Reaction of Diketoesters of Perfluorodicarboxylic Acids with Alkyl Ketones

View Full Paper
VCVictor V. ChapurkinINIlya NazarovSCSergey V. Chapurkin

Key Points

  • This research explores the synthesis of diketoesters through the reaction of perfluorodicarboxylic acids with alkyl ketones.
  • Reactions of dialkyl esters with alkyl ketones were conducted.
  • The impact of THF on the yield of tetraketones was analyzed.
  • Non-empirical MP2/6-31G* calculations were performed to examine reaction stages.
  • Diketoesters were successfully synthesized from perfluorodicarboxylic acids.
  • The addition of THF increased the yield of tetraketones.
  • Details of the reaction mechanism were elucidated based on computational calculations.

Abstract

Diketoesters were obtained by reacting dialkyl esters of perfluoroadipic and perfluoropimelic acids with alkyl ketones. The features of synthesizing polyfluorinated tetraketones via the reaction of dimethyl perfluorododecanedioate with alkyl ketones were studied. It was found that the use of THF increases the yield of tetraketones. Based on the results of non-empirical MP2/6-31G* calculations of possible stages of the process, details of the reaction mechanism were discussed.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Chapurkin et al. (2026) studied this question.

synapsesocial.com/papers/699f95a81bc9fecf3dab3b13https://doi.org/10.1134/s1070363225603898
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Catalytic Synthesis of Fluoroalkyl Ketones2024 · 2 citations
  2. 2Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry2020 · 46 citations
  3. 3Ab initio effective core potentials for molecular calculations. Potentials for the transition metal atoms Sc to Hg1985 · 13,783 citations
  4. 4Synthesis of Perfluorinated Dioxo Esters from Dimethyl Perfluoroadipate2002 · 3 citations
  5. 5ChemInform Abstract: Synthesis and Intramolecular Cyclization of Polyfluoroalkyl Substituted Bis‐β‐diketones.1998 · 1 citations