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February 27, 2026JAMA Network Open7 citationsOpen Access

Recommendations for the Deprescribing of Psychotropic Medications

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JGJoseph F. GoldbergRMR. S. McIntyreHSHolly A. Swartz

Key Points

  • The aim is to outline circumstances for the selective elimination of psychotropic medications and to advocate for empirical trials.
  • Consensus approach used by a Task Force to identify suitable conditions for deprescribing.
  • Review of clinical scenarios warranting the cessation of certain psychotropic medications.
  • Emphasis on the need for systematic assessment of deprescribing protocols.
  • Identification of specific clinical indications for deprescribing psychotropic medications.
  • Need for empirical trials to determine the safety and efficacy of deprescribing methods.

Abstract

Through this Consensus Statement, the Task Force identified circumstances in which the selective elimination of certain psychotropic medications may be clinically indicated. Empirical trials are needed to assess the implementation of deprescribing protocols and gauge their safe, effective, and acceptable outcomes.

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Cite This Study

Goldberg et al. (2026) studied this question.

synapsesocial.com/papers/69a1344fed1d949a99abe073https://doi.org/10.1001/jamanetworkopen.2026.0043
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