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February 27, 2026JACC Case Reports0 citationsOpen Access

Debulking of the Mitral Valve

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TKTanja KückenNHNora HuangFHFrank Hölschermann

Key Result

Transseptal aspiration safely debulked mitral valve thrombotic or infective masses in high-risk nonsurgical patients using large-bore catheters and cerebral protection.

Key Points

  • To evaluate the feasibility and safety of debulking mitral valve-adherent masses in high-risk nonsurgical patients.
  • Utilized large-bore steerable catheters for the procedure.
  • Employed a cerebral protection system to minimize risk during aspiration.
  • Targeted thrombotic or infective masses on the mitral valve.
  • Successfully performed transseptal aspiration on left-sided mitral valve masses.
  • Indicated that both thrombotic and infective masses can be safely debulked.

Structured PICO

Does transseptal aspiration safely debulk mitral valve-adherent masses in high-risk nonsurgical patients?

P
Population
High-risk nonsurgical patients with left-sided mitral valve-adherent masses (thrombotic or infective)
I
Intervention
Transseptal aspiration using large-bore steerable catheters and a cerebral protection system
O
Outcome
Technical feasibility and safety of debulkingsafety

Transseptal aspiration using large-bore catheters and cerebral protection offers a feasible and safe debulking option for mitral valve masses in high-risk, non-surgical patients.

Abstract

Transseptal aspiration of left-sided mitral valve-adherent masses is technically feasible in high-risk nonsurgical patients using large-bore steerable catheters and a cerebral protection system. This series suggests that thrombotic or infective masses on the mitral valve can be safely debulked through transseptal aspiration.

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Cite This Study

Kücken et al. (2026) studied this question. Transseptal aspiration safely debulked mitral valve thrombotic or infective masses in high-risk nonsurgical patients using large-bore catheters and cerebral protection.

synapsesocial.com/papers/69a134b8ed1d949a99abe315https://doi.org/10.1016/j.jaccas.2026.107059
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