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Synapse
February 27, 2026Infectious Diseases and Therapy0 citationsOpen Access

Preparing for Tuberculosis Vaccine M72/AS01E Implementation: A Global Demand Forecast and Key Influential Factors

JKJudith KallenbergDMDominique MileaTBThomas Breuer

Key Points

  • This research aims to predict the global demand for the tuberculosis vaccine M72/AS01E and identify critical factors for successful implementation.
  • Developed a demand forecasting model for the M72/AS01E vaccine.
  • Incorporated stakeholder feedback, including vaccine suppliers.
  • Scheduled updates for the model based on new data and country plans.
  • Identified essential factors influencing the vaccine's demand.
  • Emphasized the importance of coordination among stakeholders to prevent access delays.
  • Highlighted the need for timely access to funding and policy recommendations.

Abstract

M72/AS01E has the potential to reduce the TB burden worldwide. Successful vaccine introduction requires early and coordinated planning, with detailed demand forecasting refined over time. The model will be updated as new data and country implementation plans emerge. To avoid access delays, continued collaboration among key stakeholders, including vaccine suppliers, and early visibility on policy recommendations and domestic and donor funding availability will be critical in the coming years.

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Cite This Study

Kallenberg et al. (2026) studied this question.

synapsesocial.com/papers/69a134fbed1d949a99abe6b4https://doi.org/10.1007/s40121-026-01319-2
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