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February 27, 20261 citations

Insights into omalizumab use in Auckland City Hospital's immunology 2023 chronic spontaneous urticaria cohort.

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NTNathaniel TriffittKLKaren L. Lindsay

Key Points

  • This review aims to evaluate the effectiveness of omalizumab in managing chronic spontaneous urticaria (CSU).
  • Reviewed omalizumab use in CSU at Auckland City Hospital in 2023.
  • Analyzed baseline investigations and treatment outcomes.
  • Examined associations between C-reactive protein levels and treatment dosages.
  • High rates of baseline investigations were observed.
  • Raised C-reactive protein levels associated with higher omalizumab doses.
  • Lower C-reactive protein linked to CSU remission.
  • Most patients experienced angioedema and had a history of atopy.

Abstract

This review of omalizumab use in chronic spontaneous urticaria (CSU) in Auckland City Hospital's immunology department in 2023 showed that rates of baseline investigations were high but did not clearly improve CSU management. There were associations between raised C-reactive protein and higher doses of omalizumab, and lower C-reactive protein and CSU remission. Most patients had angioedema and atopy. Median symptom duration was 5 years and the majority needed at least 1 year of omalizumab treatment. Fewer Māori/Pasifika patients in this cohort may reflect barriers to accessing health care.

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Cite This Study

Triffitt et al. (2026) studied this question.

synapsesocial.com/papers/69a1355fed1d949a99abf386https://doi.org/10.1111/imj.70354
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