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February 27, 2026SHILAP Revista de lepidopterología2 citationsOpen Access

Management of nontuberculous mycobacterial Pulmonary disease refractory to guideline-based therapy: A systematic review.

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DMDiana Moreira-SousaBMB. MartinsAAA. Pedro Aguiar

Key Points

  • To explore effective management strategies for patients with refractory NTM-PD.
  • Conducted a systematic review of existing literature
  • Analyzed treatment intensification, supportive measures, and symptom control
  • Examined clinical, microbiological, and radiological factors
  • Identified knowledge gaps in managing NTM-PD
  • Highlighted the necessity for individualized treatment approaches
  • Suggests that no standardized treatment currently exists

Abstract

This systematic review underscores the complexity of managing refractory NTM-PD, highlighting the role of treatment intensification, symptom control, supportive measures, and knowledge gaps. While no standardised approach exists, individualised strategies incorporating clinical, microbiological, and radiological factors remain essential for optimising patient outcomes.

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Cite This Study

Moreira-Sousa et al. (2026) studied this question.

synapsesocial.com/papers/69a1359eed1d949a99abfb81https://doi.org/10.1080/25310429.2026.2632467
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