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February 28, 2026Vaccine Insights0 citations

Designing durability: T follicular helper cells and the future of vaccine-induced immunity

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NGNimesh Gupta

Key Points

  • The discussion aims to understand how T follicular helper cells contribute to long-lasting antibody responses and their implications for vaccine development.
  • Interview with Nimesh Gupta, focusing on T follicular helper cells and their role in immunity.
  • Analysis of emerging correlates of protection related to vaccine-induced responses.
  • Review of advanced immuno-profiling techniques for guiding vaccine development.
  • Highlights the significance of T follicular helper cells in forming durable antibody responses.
  • Identifies potential correlates of protection that can inform vaccine efficacy.
  • Suggests that Tfh-based assays may become essential in practical vaccine design and evaluation.

Abstract

Ashling Cannon (Editor, Vaccine Insights) speaks with Nimesh Gupta (Chief, Vaccine Immunology Laboratory, National Institute of Immunology, India) about the role of T follicular helper cells in shaping durable antibody responses, emerging correlates of protection, and how advanced immuno-profiling could inform future vaccine development and evaluation. “...Tfh-based assays will evolve into practical tools for guiding vaccine design and development in the years ahead.”

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Cite This Study

Nimesh Gupta (2026) studied this question.

synapsesocial.com/papers/69a286c90a974eb0d3c01f5ehttps://doi.org/10.18609/vac.2026.006
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