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February 28, 2026Journal of Clinical Medicine2 citationsOpen Access

Laser-Based Therapies in Rosacea: A Comprehensive Review of Mechanisms, Clinical Efficacy, and Future Directions

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JSJagoda SzwachWroclaw Medical UniversityMSMaciej SzwajkowskiWroclaw Medical UniversityJMJulia MakówkaWroclaw Medical University

Key Points

  • This review aims to summarize the mechanisms and clinical efficacy of laser therapies for rosacea.
  • Reviewed the application of various laser types in rosacea treatment.
  • Analyzed clinical efficacy and adverse effects of treatments.
  • Compared the effectiveness of pulsed dye lasers, KTP, IPL, Nd:YAG, CO2, and Er:YAG lasers.
  • Pulsed dye laser is identified as the gold standard in treating rosacea.
  • KTP and IPL lasers show comparable clinical results with fewer side effects.
  • Nd:YAG laser is effective for deeper skin lesions in advanced rosacea.
  • Ablative lasers, CO2 and Er:YAG, are used for severe forms like rhinophyma.

Abstract

Rosacea is a chronic inflammatory skin disease characterized by erythematous, papular, and pustular lesions. Treatment for rosacea is tailored to the type and severity of lesions and the individual needs of the patient. The primary therapy involves topical and systemic treatments. Laser therapy is also an effective method. This review summarizes current knowledge on the application of pulsed dye lasers (PDLs), potassium titanyl phosphate (KTP) lasers, intense pulsed light (IPL), neodymium-doped yttrium aluminum garnet (Nd:YAG) lasers, carbon dioxide (CO2) lasers, and erbium-doped yttrium aluminum garnet (Er:YAG) lasers in the treatment of rosacea. Research confirms that the PDL remains the gold standard, demonstrating excellent clinical efficacy. The KTP and IPL lasers provide comparable outcomes, with relatively fewer adverse effects. Due to its greater depth of penetration, the Nd:YAG laser is used to treat lesions in the deeper layers of the skin. In advanced forms of rosacea, such as rhinophyma, ablative lasers, including CO2 and Er:YAG, are employed. This review summarizes the mechanisms of action, therapeutic applications, and adverse effects associated with the use of various laser types in the management of rosacea.

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Cite This Study

Szwach et al. (2026) studied this question.

synapsesocial.com/papers/69a287570a974eb0d3c02ec0https://doi.org/10.3390/jcm15051771
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