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May 23, 2022Neurology140 citationsOpen Access

Effect of Race on Prediction of Brain Amyloidosis by Plasma Aβ42/Aβ40, Phosphorylated Tau, and Neurofilament Light

SSSuzanne E. SchindlerTKThomas K. KarikariNANicholas J. Ashton

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Abstract

Models predicting brain amyloidosis using a high-performance plasma Aβ42/Aβ40 assay may provide an accurate and consistent measure of brain amyloidosis across AA and NHW groups, but models based on plasma p-tau181, p-tau231, and NfL may perform inconsistently and could result in disproportionate misdiagnosis of AA individuals.

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Schindler et al. (2022) studied this question.

synapsesocial.com/papers/69a39d55f617f9b5a099dc71https://doi.org/10.1212/wnl.0000000000200358
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