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March 1, 20261 citations

Effects and Dose-Response Relationship of High-Intensity Interval Training on Cardiometabolic Risk in Individuals With Overweight and Obesity: A Systematic Review and Meta-Analysis.

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GZGaoning ZhangMZMingjing ZhangPPPeiQiang Peng

Key Result

High-intensity interval training effectively reduces cardiometabolic risk factors in overweight and obese individuals, showing a preliminary dose-response relationship.

Key Points

  • This research aims to evaluate the effects of high-intensity interval training on cardiometabolic risk in individuals with overweight and obesity.
  • Conducted a systematic review and meta-analysis
  • Evaluated the effectiveness of HIIT on cardiometabolic risk and lipid metabolism
  • Analyzed training variables and their impacts on outcomes
  • HIIT significantly reduces cardiometabolic risk in individuals with overweight and obesity
  • A preliminary dose-response relationship was noted, indicating optimal training variables may influence outcomes
  • Future protocols should be optimized for sustained benefits

Structured PICO

Does High-Intensity Interval Training (HIIT) reduce cardiometabolic risk in individuals with overweight and obesity?

P
Population
Individuals with overweight and obesity
I
Intervention
High-Intensity Interval Training (HIIT)
O
Outcome
Cardiometabolic risk (CRF, lipid metabolism)surrogate

High-Intensity Interval Training (HIIT) effectively improves cardiometabolic risk factors, including cardiorespiratory fitness and lipid metabolism, in individuals with overweight and obesity, demonstrating a preliminary dose-response relationship.

Limitations

  • Lack of optimized protocols
  • Unconfirmed sustained benefits

Abstract

HIIT is an effective strategy to reduce cardiometabolic risk (CRF, lipid metabolism) in individuals with overweight and obesity, with a preliminary dose-response relationship observed between training variables and outcomes. Future studies should optimize protocols and confirm sustained benefits.

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Cite This Study

Zhang et al. (2026) studied this question. High-intensity interval training effectively reduces cardiometabolic risk factors in overweight and obese individuals, showing a preliminary dose-response relationship.

synapsesocial.com/papers/69a3d800ec16d51705d2e7b7https://doi.org/10.1111/obr.70115
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