Radioguided Occult Lesion Localization (ROLL) and Radioactive Seed Localization (RSL) versus Wire-guided Localization (WGL) in Breast-conserving Surgery for Non-Palpable Breast Cancer: a Systematic Review and Meta-analysis of Randomized Controlled Trials

Key Points

• Radioguided localization techniques improve surgical outcomes compared to traditional wire-guided localization.
• In meta-analysis, patients undergoing radioguided procedures showed a decrease in re-excision rates by approximately 30%.
• Systematic review assessed randomized controlled trials across multiple healthcare centers, ensuring diverse patient data.
• Findings suggest a shift towards radioguided techniques may enhance breast-conserving surgery effectiveness, but require further validation.