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March 3, 2026Rapid Communications in Mass Spectrometry1 citationsOpen Access

In Vitro Metabolism and Analytical Characterization of SLU‐PP‐332 and SLU‐PP‐915: Novel Pan‐ERR Agonists With Doping Potential

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TMTristan MöllerOKOliver KrugMTMario Thevis

Key Points

  • Analysis reveals the metabolic pathways for SLU-PP-332 and SLU-PP-915, both pan-ERR agonists with potential doping applications.
  • The study highlights that these new compounds could be misused for enhancing athletic performance, raising ethical concerns.
  • Metabolism studies provide critical insights into how rapidly the compounds are processed in vitro, potentially influencing their effects.
  • Identifying the characteristics of these substances may inform guidelines to combat their misuse in sports and athletics.

Abstract

The results obtained in this study gave an in-depth view into the analysis and in vitro metabolism of the newly developed pan-ERR agonists SLU-PP-332 and SLU-PP-915. This may help to uncover the illicit use of these novel compounds as potential performance-enhancing substances.

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Cite This Study

Möller et al. (2026) studied this question.

synapsesocial.com/papers/69a75ae8c6e9836116a215f3https://doi.org/10.1002/rcm.70039
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