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March 3, 2026Journal of NeuroimmunologyOpen Access

Bilateral optic neuritis preceding a Baló concentric sclerosis lesion: A case report and literature review

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Authors

DADavid F. Alfonso-CedeñoLMLorena Medina-LozanoPGPaula V. Gaete

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Overview

Case report reveals challenges in diagnosing Baló concentric sclerosis, suggesting B-cell-depleting therapy effectiveness.

Key Points

  • Initial imaging revealed no abnormalities, complicating the diagnosis despite significant symptoms.
  • Cerebrospinal fluid analysis showed type 1 oligoclonal bands, indicating a demyelinating process.
  • Treatment with plasmapheresis improved bulbar symptoms, showcasing its role in managing severe cases.
  • Rituximab therapy led to clinical stability, highlighting a potential intervention in BCS.

Cite This Study

Alfonso-Cedeño et al. (2026) studied this question.

synapsesocial.com/papers/69a75b35c6e9836116a221d3https://doi.org/10.1016/j.jneuroim.2026.578874
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