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March 3, 2026The American Journal of Gastroenterology0 citations

Model for End-Stage Liver Disease-Lactate and Lactate Clearance in Critically Ill Cirrhosis Patients With Sepsis

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RSRehma ShabbirLGLuis Garrido-TrevinoJOJacqueline G. O’Leary

Key Points

  • Early reduction in lactate levels by one-third correlates with 30-day mortality in cirrhosis patients.
  • Combining MELD-LA and lactate clearance enhances risk stratification for this patient group.
  • Assessment relies on monitoring lactate levels to inform clinical management in the ICU.
  • Understanding these markers may improve outcomes for critically ill patients suffering from sepsis.

Abstract

Early reduction in initial LA by one-third predicts 30-day mortality and may indicate treatment response in cirrhosis patients with sepsis in the ICU. Combining MELD-LA and LA clearance early enables better risk stratification and informs management.

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Cite This Study

Shabbir et al. (2026) studied this question.

synapsesocial.com/papers/69a75b36c6e9836116a22224https://doi.org/10.14309/ajg.0000000000003934
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